Current Residents
Solving the Question of Inflammation or Sepsis Hastily–Serial Management Study
Timecourse study with serial measurements to examine correlation between test results
and patient trajectory. Currently enrolling in conjunction with Cytovale.
Solving the Question of Inflammation or Sepsis Hastily–Integration into the ER
Pragmatic use study to determine how and when the ED will order ISI with subsequent
decisional impacts. Currently enrolling in conjunction with Cytovale.
Pragmatic Trial Examining Oxygenation Prior to Intubation
Understanding the impact of preoxygenation modes prior to intubation. Currently enrolling
in conjunction with the Pragmatic Critical Care Research Group.
A Prospective Cohort to Assess Performance of Video Oximetry
Confirming the accuracy of video oximetry compared to pulse oximetry and blood gas
analysis. Currently enrolling in conjunction with the University of South Australia
Johns Hopkins Activity and Mobility Promotion
Improving patient outcomes through early and systematic activity and mobility. Currently
enrolling in Phase 2 in conjunction with Johns Hopkins University.
Longitudinal Study of Undergraduate Baseball Pitchers
Assess for MRI and exam findings as risk factors for dominant shoulder and/or elbow
injuries of elite college pitchers. Observational study in conjunction with LSU Sports Medicine.

PAST PROJECTS
SQuISH
Solving the Question of Inflammation versus Sepsis Hastily — Attempting to develop a point-of-care diagnostic test that can be performed quickly at the initial suspicion of sepsis
O'Neal HR Jr, Sheybani R, Caffery TS, Hamer D, Laperouse LM Jr, Musso MW, O'Neal CS, Tse HTK, Shah AM, Thomas CB. Assessment of a cellular host response test to risk-stratify suspected COVID-19 patients in the emergency department setting. PLoS ONE 2022; 17(3): e0264220.
O'Neal HR Jr, Sheybani R, Caffery TS, Musso MW, Hamer D, Alwood SM, Berlinger MS, Jagneaux T, LaVie KW, O'Neal CS, Sanchez MA, Walker MK, Shah AM, Tse HTK, Thomas CB. Assessment of a cellular host response test as a sepsis diagnostic for a suspected infection population in the emergency department setting. Crit Care Exp 2021; 3(6): e0460.
Guillou L, Sheybani R, Jensen AE, Di Carlo D, Caffery TS, Thomas CB, Shah AM, Tse HTK, O'Neal HR Jr. Development and validation of a cellular host response test as an early diagnostic for sepsis. PLoS ONE 2021; 16(4): e0246980.
MENDS2
Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients with Acute Respiratory Failure